Juan Astigueta-Pérez, Escuela de Medicina Humana, Universidad Privada Antenor Orrego; Departamento de Cirugía Oncológica, Instituto Regional de Enfermedades Neoplásicas Norte; Trujillo, Perú
Milagros Abad-Licham, Escuela de Medicina Humana, Universidad Privada Antenor Orrego; Departamento de Patología Oncológica, Instituto Regional de Enfermedades Neoplásicas Norte; Centro de Excelencia en Patología Oncológica. Trujillo, Perú
Jesús Gonzáles-Zaravia, Departamento de Cirugía Oncológica, Instituto Regional de Enfermedades Neoplásicas Norte, Trujillo, Perú
Background: The intraoperative study is a main diagnostic procedure for decision making in urological oncology. There are few publications, and they are mainly related to the evaluation of surgical margins. Objective: To determine the role of the intraoperative study (IS) in patients with uro-oncological neoplasms. Method: Analytical, observational, cross-sectional, diagnostic test study. The anatomical-pathological results of patients treated in the Urology Service of the Instituto Regional de Enfermedades Neoplásicas Norte were evaluated, in the period 2010-2019, in which the result of the IS was compared with that obtained in the histological study (HS) processed in paraffin (gold standard). Results: Sixty-six EIO with their respective HE were included, 16 (24%) patients were females and 50 (76%) males. The average age was 52.1, with a range between 17 and 84 years. Of the total EIO, 37 (56.1%) were positive for malignant neoplasm, 28 (42.4%) were negative, and 1 (1.5%) could not be defined. In HE, the diagnosis was confirmed in 62 cases (95.4%) and discrepancies were found in 3 (4.6%). The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of the EIO were 94.7, 96.3, 97.3, 92.9, and 95.4%, respectively; likewise, the positive and negative likelihood ratios were 25.6 and 0.05. Conclusion: EIO in uro-oncology is useful and highly reliable in decision making during surgery.
Keywords: Intraoperative study. Cytology. Frozen section. Urologic neoplasms.
